Tuesday, September 22, 2020

COVID-19 Lab-Made Antibodies Could Serve As Protection Until A Vaccine – Veterans Today

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Cryo-EM reconstructions show how two different antibodies (blue) bind in different ways to the spike protein of the SARS-CoV-2 virus. David Ho / Columbia University Irving Medical Center.

Potent neutralizing antibodies target new regions of coronavirus spike

NIH Research Matters

Scientists are racing to develop approaches to protect against SARS-CoV-2, the virus that causes COVID-19. Several vaccine candidates are now in clinical trials. Another possible approach involves antibodies, proteins made by the immune system to fight infection. Antibodies work to neutralize viruses by binding to their surface and blocking entry into a person’s cells.

Antibodies that neutralize SARS-CoV-2 could be produced in a lab and given to people to treat infection. These lab-made antibodies, called monoclonal antibodies, could also serve as a prevention option until a vaccine is available. Vaccines prompt the immune system to make antibodies against a virus. Monoclonal antibodies are delivered directly to the body, through injection or intravenous infusions, and circulate in the blood.

Monoclonal antibodies are currently used to treat a variety of conditions, including rheumatoid arthritis, Crohn’s disease, and cancer. They may be the only option for older adults and others who can’t develop or maintain an adequate immune response after vaccination. But researchers must first identify powerful antibodies to neutralize SARS-CoV-2.

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Carol graduated from Riverside White Cross School of Nursing in Columbus, Ohio and received her diploma as a registered nurse. She attended Bowling Green State University where she received a Bachelor of Arts Degree in History and Literature. She attended the University of Toledo, College of Nursing, and received a Master’s of Nursing Science Degree as an Educator.

She has traveled extensively, is a photographer, and writes on medical issues. Carol has three children RJ, Katherine, and Stephen – two daughters-in-law; Suzy and Katie – two granddaughters; Isabella Marianna and Zoe Olivia – and one grandson, Alexander Paul. She also shares her life with husband Gordon Duff, many cats, and two rescue pups.


Carol’s Archives 2009-2013

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